Peter & Amadeus befriend robotics prodigy Hiro Hamada & his robot Baymax, who are visiting New York to take part in a robotics competition. Just as Peter & Amadeus expect to hang out with their two new friends, Hiro & Baymax are called back home to help their friends. Spider Man & the Iron Spider follow them to their hometown, San Fransokyo; there, they team up with Hiro & Baymax's team, Big Hero 6, to fight against undisputed bot-fighter champion Mr. Yama & his gang of criminals.
Appearing in Crossover
- Spider-Man (Peter Parker)
- Iron Spider (Amadeus Cho)
- Big Hero 6 (First & only appearance)
- Mr. Yama (First & only appearance)
- Kamikaze (First & only appearance)
- Sumo (Jun Tenta) (First & only appearance)
- Fujitas (First & only appearance)
- Little Yama (First & only appearance)
- The ending credits uses the song "Immortals", which is the lead single for the Big Hero 6 Soundtrack.